during and for at least 1 menstrual cycle after treatment with Rasuvo for females.for a minimum of 3 months after treatment with Rasuvo for males.
Pregnancy should be avoided if either partner is receiving Rasuvo:
Contraception should be used by both females and males while taking Rasuvo. A pregnancy test should be performed before starting Rasuvo. Women who are pregnant or who plan to become pregnant must not take Rasuvo. Women who are pregnant are at increased risk for death of the baby and for birth defects in the baby.
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Call your doctor right away if you have any of the following symptoms of organ toxicity: vomiting, neck stiffness, diarrhea, paralysis, mouth sores, irritability, fever, sleepiness, confusion, problems with coordination, weakness, dry cough, temporary blindness, trouble breathing, seizures, severe skin rash, headache, and back pain. Your doctor will do blood tests and other types of tests before you take and while you are taking Rasuvo to check for signs and symptoms of organ toxicity. Types of organ toxicity can include: gastrointestinal, nerve, bone marrow, lung, liver, kidneys, immune system, and skin. People who use methotrexate for the treatment of cancer, psoriasis, or rheumatoid arthritis, have an increased risk of death from organ toxicity. Rasuvo can cause serious side effects that can lead to death, including: Important Safety Information, Including Boxed Warning, for Rasuvo What is the most important information I should know about Rasuvo? This product includes the following Boxed Warning: Your doctor will prescribe a different way to take methotrexate if you need to take methotrexate by mouth or in some other way. Rasuvo should not be used for the treatment of children with psoriasis. Rasuvo should not be used for the treatment of cancer.